Pathological conditions predisposing to infertility and gynaecological neoplasia

Shift work and pathological conditions

Shift work exerts major influences on the physiological functions of the human body. These are primarily mediated by the disruption of circadian rhythms since most body functions are circadian rhythmic. Next to the disturbances caused by changes in the circadian system, shift work has also been suggested to be related to a number of other health disorders. The present study summarizes recently ...

Clinical and Pathological Heterogeneity of Cervical Intraepithelial Neoplasia Grade 3

OBJECTIVE Cervical intraepithelial neoplasia grade 3 (CIN3), the immediate cervical cancer precursor, is a target of cervical cancer prevention. However, less than half of CIN3s will progress to cancer. Routine treatment of all CIN3s and the majority of CIN2s may lead to overtreatment of many lesions that would not progress. To improve our understanding of CIN3 natural history, we performed a d...

NEOPLASIA ALK 1 Lymphoma : Clinico - Pathological Findings and Outcome

A distinct pathologic entity (ALK1 lymphoma) that is characterized by expression of the anaplastic lymphoma kinase (ALK) protein has recently emerged within the heterogeneous group of CD301 anaplastic large-cell lymphomas. Information on clinical findings and treatment outcome of ALK1 lymphoma is still limited, and no data are available concerning the value of the International Prognostic Index...

Tuberculous endometritis: its association with infertility and other gynaecological complaints in Indian women

Elastin peptides in aging and pathological conditions.

Elastin is the protein responsible for the resilience of vertebrate tissue. It is an extremely stable protein deposited during the early stages of life and experiencing almost no renewal. As a consequence, it can be considered that each individual has an elastin capital for life. Despite its extreme stability, elastin can be degraded by several enzymes termed elastases. Elastases are among the ...